Pisa has regular trains to and from Florence (usually three per hour), to and from Lucca (usually every hour) and is also accessible by bus, and has an international airport.
Pisa Centrale is the main train station of Pisa. Rome to Genova trains stop at Pisa Centrale. If you are planning an in-route visit to Pisa, it is also convenient since Pisa Centrale has Left Luggage service open from 6:00 AM to 9:00PM. Each baggage deposited costs ?3.00 for 12 hours.